CELLtech is White Cross;sIn addition to serving as the site of oxidative phosphorylation, it is now clear that mitochondria regulate many cellular functions, in part by producing reactive oxygen species that signal the adaptive response to environmental stress and injury. 1 Excess production of mitochondria‐derived oxidants, however, may have maladaptive effects. 2 , 3 There is growing evidence that disturbances of mitochondrial function, including increased oxidant production and altered mitochondria dependent signaling, contribute to the pathogenesis of vascular disease in atherosclerosis and other cardiovascular risk factors. 1 , 4 , 5
Vascular Function and Blood Pressure in Patients With Coronary Artery Disease
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